| 发明名称 |
CD40L EXPRESSING MAMMALIAN CELLS AND THEIR USE |
| 摘要 |
Herein is reported a co-cultivation system for co-cultivating a pool of rabbit B-cells or single deposited rabbit B-cells wherein cells CD40L expressing CHO cells are used as feeder in the presence of IL-2 and IL-21. |
| 申请公布号 |
US2014315252(A1) |
申请公布日期 |
2014.10.23 |
| 申请号 |
US201214360048 |
申请日期 |
2012.11.21 |
| 申请人 |
Hoffmann-La Roche Inc. |
发明人 |
Endl Josef;Fischer Jens;Kern Peter;Offner Sonja;Platzer Josef;Seeber Stefan |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for producing an antibody comprising the step of co-cultivating a rabbit B-cell with a rabbit CD40L expressing mammalian cell in the presence of IL-2 and IL-21. |
| 地址 |
Little Falls NJ US |
