发明名称 |
Methods and Compositions for Treatment of Diabetes and Related Disorders |
摘要 |
The present invention provides a method of stimulating growth of a pancreatic islet beta cell and/or enhancing glucose stimulated insulin secretion of a pancreatic islet beta cell, comprising delivering to the cell an exogenous nucleotide sequence encoding Nkx6.1 transcription factor. |
申请公布号 |
US2014315984(A1) |
申请公布日期 |
2014.10.23 |
申请号 |
US201414164865 |
申请日期 |
2014.01.27 |
申请人 |
Duke University |
发明人 |
Newgard Christopher B.;Schisler Jonathan C. |
分类号 |
C07K14/47 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
1. A method of stimulating growth of a pancreatic islet beta cell, comprising delivering to the cell an exogenous nucleotide sequence encoding a Nkx6.1 protein or an active fragment thereof. |
地址 |
Durham NC US |