摘要 |
<p>PROBLEM TO BE SOLVED: To provide a method for inducing synthesis of NADin subjects.SOLUTION: The method comprises administration of a therapeutically effective amount of resveratrol or a functionally equivalent analog or derivative of resveratrol to a subject. Synthesis of NADincreases the activity of poly(ADP-ribose)polymerase(PARP) enzyme and sirtuin enzyme. The PARP enzyme is PARP-1 or PARP-2. The sirtuin enzyme is selected from the group consisting of SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6 and SIRT7.</p> |