发明名称 |
CIRCULATING BMEC AND RELATED CELLS AS BIOMARKERS OF CNS DISEASES ASSOCIATED WITH THE BLOOD-BRAIN-BARRIER DISORDERS |
摘要 |
Described herein are processes, assays and methods for detecting damage to the blood-brain barrier by assaying the levels of any one or more of cBMEC, EPC and/or UCHL1. An increase in the levels of cBMEC, EPC and/or UCHL1 in a sample obtained from the subject is indicative of damage to the blood-brain barrier. |
申请公布号 |
WO2014124174(A3) |
申请公布日期 |
2014.10.23 |
申请号 |
WO2014US15158 |
申请日期 |
2014.02.06 |
申请人 |
CHILDREN'S HOSPITAL LOS ANGELES |
发明人 |
HUANG, SHENG-HE;JONG, AMBROSE;CHI, FENG;WANG, LIN |
分类号 |
G01N33/53;A61K39/00;C12Q1/02;G01N33/567 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|