A process for the preparation of copolymer - 1 (Cop-I), composed of L-alanine, L-lysine, L-glutamic acid and L-tyrosine-drug for the treatment of multiple sclerosis

摘要

A process for the synthesis of copolymer-1 composed of L-alanine, LHysine, L-glutamic acid and L-tyrosine for the treatment of multiple sclerosis.The molecular weight of copolymer-1 is between 8-19 KDa. Process is initiated by supported dialkyl amine. The copolymer-1 of the invention has acid content of less than 1%.