| 发明名称 |
Cocrystalline DHEA Formulations |
| 摘要 |
A cocrystalline DHEA composition with at least one additional coformer is disclosed for therapeutic formulations. The cocrystalline DHEA/coformer formulation including at least one coformer chosen from the group consisting of glutaric acid, maleic acid, tartaric acid, fructose, and wherein the L-isomer of tartaric acid and the D-isomer of fructose are utilized. The cocrystalline DHEA/coformer formulations include certain excipients as a solubilizer or inhibitor. |
| 申请公布号 |
US2014315833(A1) |
申请公布日期 |
2014.10.23 |
| 申请号 |
US201414257594 |
申请日期 |
2014.04.21 |
| 申请人 |
University of Houston System |
发明人 |
Berkenstam Anders;Kuczynski Edward;Andersson Alf S.;Gustafsson Jan-Ake;Filgueira Carly Sue |
| 分类号 |
A61K47/48;C07C49/727 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
DHEA, wherein the DHEA is a polymorph form I (FI) or polymorph form II (FII); and a crystalline coformer. |
| 地址 |
Houston TX US |
