发明名称 2,2'-FUROIN DERIVATIVES AND THEIR USE FOR SKIN LIGHTENING
摘要 The invention relates to the use of compounds of the formula (I), in which R1, R2, m and n have the meanings indicated in the Claims, and/or physiologically acceptable salts, tautomers, stereoisomers and/or solvates thereof, including mixtures thereof in all ratios, for the inhibition of tyrosinase and for lightening the skin. The invention also relates to the use of the compounds of the formula (I) in the prophylaxis, therapy or progress control of pigment disorders of the skin. The invention furthermore relates to preparations comprising the compounds of the formula (I) in combination with at least one further active compound and to a process for the preparation of the preparations by mixing the compounds of the formula (I) with a vehicle which is physiologically acceptable for topical applications.
申请公布号 EP2616040(B1) 申请公布日期 2014.10.22
申请号 EP20110752111 申请日期 2011.08.18
申请人 MERCK PATENT GMBH 发明人 SCHEURICH, RENÉ, PETER
分类号 A61K8/49 主分类号 A61K8/49
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