| 发明名称 |
COMPOSITIONS OF BUPRENORPHINE AND MU-OPIOID RECEPTOR ANTAGONISTS |
| 摘要 |
The invention relates to a composition comprising buprenorphine and a μ opioid receptor antagonist, wherein the composition is characterized by an Agonist Antagonist Activity Index (AAnAI) of between about 0.7 and about 2.2; wherein; AAnAI = [ C max ( BUB ) BC 30 ] [ C max ( ANTAGONIST ) IC 30 ] . |
| 申请公布号 |
EP2790702(A1) |
申请公布日期 |
2014.10.22 |
| 申请号 |
EP20120830900 |
申请日期 |
2012.12.14 |
| 申请人 |
ALKERMES PHARMA IRELAND LIMITED |
发明人 |
DEAVER, DANIEL;EHRICH, ELLIOT |
| 分类号 |
A61K31/485;A61K45/06;A61P25/04;A61P25/22;A61P25/24 |
主分类号 |
A61K31/485 |
| 代理机构 |
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