发明名称 |
Pyridyl-vinyl-pyrazolo-chinolines as PAR1 inhibitors |
摘要 |
<p>The disclosure relates to compounds of formula I: wherein the groups R1, R2, R3, R4, R5 and X are as defined in the disclosure, having antithrombotic activity, which in particular inhibits the protease-activated receptor 1 (PAR1). The disclosure further relates to methods for producing the same and to the use thereof as a pharmaceutical product.</p> |
申请公布号 |
EP2558462(B1) |
申请公布日期 |
2014.10.22 |
申请号 |
EP20110714317 |
申请日期 |
2011.04.14 |
申请人 |
SANOFI |
发明人 |
SCHOENAFINGER, KARL;STEINHAGEN, HENNING;SCHEIPER, BODO;HEINELT, UWE;WEHNER, VOLKMAR;HERRMANN, MATTHIAS;MAUGER, JACQUES;SAFAR, PAVEL |
分类号 |
C07D471/04;A61K31/444;A61P9/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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