发明名称 |
Modified parvovirus useful for gene silencing |
摘要 |
<p>Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an expressible target specific nucleic acid, preferably an shRNA expression cassette. Also described are cells or organisms comprising said parvovirus.</p> |
申请公布号 |
EP2620503(B1) |
申请公布日期 |
2014.10.22 |
申请号 |
EP20120000554 |
申请日期 |
2012.01.27 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM |
发明人 |
MARCHINI, ANTONIO;ROMMELAERE, JEAN;LEUCHS, BARBARA;ILLARIONOVA, ANNA |
分类号 |
C12N15/864;A01K67/027;C12N15/113 |
主分类号 |
C12N15/864 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|