发明名称 |
PROCESS FOR PREPARING SODIUM SALTS OR POTASSIUM SALTS OF 4-HYDROXY-2-OXO-2,5-DIHYDROFURAN-3-CARBOXYLATE |
摘要 |
<p>Process for preparing sodium or potassium salts of 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylic esters, comprising the reaction of a malonic ester with potassium hydroxide to give the corresponding malonic ester potassium salt of the formula (III) which is then reacted further with a chloroacetic ester to give a compound of the formula (V) followed by a ring closure reaction in which the compound of the formula (V) is reacted with a sodium or potassium alkoxide of the formula ZOR1 where R1, R2, R3 and K are each as defined in the description.</p> |
申请公布号 |
EP2681202(B1) |
申请公布日期 |
2014.10.22 |
申请号 |
EP20120706057 |
申请日期 |
2012.02.29 |
申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
FUNKE, CHRISTIAN;FARIDA, TARANEH;BEECK, STEFAN;LUI, NORBERT;MAIWALD, BERNDT |
分类号 |
C07D307/68 |
主分类号 |
C07D307/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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