发明名称 Pancreatic cancer targets and uses thereof
摘要 The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
申请公布号 US8865413(B2) 申请公布日期 2014.10.21
申请号 US201113100902 申请日期 2011.05.04
申请人 Celera Corporation 发明人 Domon Bruno;McCaffery Ian;Narayan Vaibhav;Patterson Scott
分类号 C12Q1/00;G01N1/00;G01N33/00;G01N33/48;G01N33/53;G01N33/566;G01N33/567;G01N33/574 主分类号 C12Q1/00
代理机构 Celera Corporation 代理人 Celera Corporation
主权项 1. A method of diagnosing pancreatic cancer in a human, the method comprising detecting the level of golgi apparatus protein 1 in a sample from the human using a detection reagent that selectively binds to the golgi apparatus protein 1, and diagnosing said human as having pancreatic cancer when the level is elevated relative to a control golgi apparatus protein 1 level established for a non-cancerous sample, wherein the golgi apparatus protein 1 comprises SEQ ID NO:52.
地址 Alameda CA US