Compositions and methods for the maintenance of oral health

摘要

The invention provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oralis strains and/or one or more isolated S. uberis strains. Compositions of the invention are useful to maintain oral health, by for example treating and/or preventing one or more symptoms of dental caries, periodontitis and/or other oral cavity diseases or wounds.

主权项

1. A composition comprising: one or more biologically pure mutans streptococci strains selected from the group consisting of Streptococcus rattus, strain JH145, Streptococcus cricetus, Streptococcus mutans, Streptococcus sobrinus, Streptococcus downeii, Streptococcus macacae, and Streptococcus ferus; wherein said mutans streptococcus strains are lactate dehydrogenase-deficient; a biologically pure Streptococcus oralis strain; and a biologically pure Streptococcus uberis strain.