发明名称 Antibodies to IL-17A and uses thereof
摘要 Binding members, especially antibody molecules, for interleukin 17 (IL-17). The binding members are useful for the treatment of disorders associated with interleukin 17 such as rheumatoid arthritis.
申请公布号 US8865166(B2) 申请公布日期 2014.10.21
申请号 US200711767208 申请日期 2007.06.22
申请人 MedImmune Limited 发明人 Cochrane Duncan;Russell Caroline;Sleeman Matthew;Welsh Fraser;Langham Caroline;Needham Maurice;Dufner Patrick
分类号 A61K39/395;C07K16/24;C07K14/54;A61K39/00 主分类号 A61K39/395
代理机构 代理人
主权项 1. An isolated antibody or antibody fragment thereof for human IL-17A, wherein the antibody or antibody fragment thereof comprises a set of CDRs comprising HCDR1, HCDR2 and HCDR3, which amino acid sequences are identical to SEQ ID NOs:63, 64 and 65, respectively; and LCDR1, LCDR2 and LCDR3, which amino acid sequences are identical to SEQ ID NOs:68, 69 and 70, respectively.
地址 Cambridge GB