发明名称 |
Increasing anti-IL-1α antibodies in a subject |
摘要 |
Method of detecting individuals at risk for atherosclerosis and related vascular diseases involving the detection of IL-1α autoantibodies, as well as therapeutic methods to prevent or treat atherosclerosis and related vascular disease by administering a pharmaceutical composition comprising IL-1α autantibodies. |
申请公布号 |
US8865175(B2) |
申请公布日期 |
2014.10.21 |
申请号 |
US201213473939 |
申请日期 |
2012.05.17 |
申请人 |
XBiotech, Inc. |
发明人 |
Simard John;Bendtzen Klaus |
分类号 |
A61K39/395;G01N33/564;C07K16/24 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
Kim Stanley A. |
主权项 |
1. A method of raising the serum titer of anti-IL-1α antibodies in an individual previously determined to have a low serum titer of IL-1α autoantibodies, the method comprising the step of: administering to the individual previously determined to have a low serum titer of IL-1α autoantibodies a pharmaceutical composition which consists essentially of: antibodies that target IL-1α and a pharmaceutically acceptable vehicle. |
地址 |
Vancouver CA |