发明名称 Increasing anti-IL-1α antibodies in a subject
摘要 Method of detecting individuals at risk for atherosclerosis and related vascular diseases involving the detection of IL-1α autoantibodies, as well as therapeutic methods to prevent or treat atherosclerosis and related vascular disease by administering a pharmaceutical composition comprising IL-1α autantibodies.
申请公布号 US8865175(B2) 申请公布日期 2014.10.21
申请号 US201213473939 申请日期 2012.05.17
申请人 XBiotech, Inc. 发明人 Simard John;Bendtzen Klaus
分类号 A61K39/395;G01N33/564;C07K16/24 主分类号 A61K39/395
代理机构 代理人 Kim Stanley A.
主权项 1. A method of raising the serum titer of anti-IL-1α antibodies in an individual previously determined to have a low serum titer of IL-1α autoantibodies, the method comprising the step of: administering to the individual previously determined to have a low serum titer of IL-1α autoantibodies a pharmaceutical composition which consists essentially of: antibodies that target IL-1α and a pharmaceutically acceptable vehicle.
地址 Vancouver CA