发明名称 Water soluble film for oral administration with instant wettability
摘要 A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
申请公布号 US8865202(B2) 申请公布日期 2014.10.21
申请号 US200410771388 申请日期 2004.02.05
申请人 LTS LOHMANN Therapie-Systeme AG 发明人 Zerbe Horst Georg;Guo Jian-Hwa;Serino Anthony
分类号 A61K8/73;A61K8/72;A61K47/00;A61K47/38;A61Q11/00;A61K31/44;A61K8/02;A61K9/00;A61K8/39;A61K8/81;A61K8/92;A61K8/90;A61K8/49 主分类号 A61K8/73
代理机构 Wenderoth, Lind & Ponack, L.L.P. 代理人 Wenderoth, Lind & Ponack, L.L.P.
主权项 1. A composition applicable to the oral cavity, for releasing active substances in the oral cavity, wherein the composition comprises polyvinyl pyrrolidone and hydroxypropylmethyl cellulose, a nicotine salt, and, a water-dispersible methyl methacrylate copolymer, wherein said composition exhibits instant wettability which causes the composition to soften immediately after application to the oral mucosa, followed by rapid dissolution or disintegration of the composition, and said composition is a dry film that is orally applicable and that has a thickness of not more than 70 μm.
地址 Andernach DE