发明名称 |
BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATMENT OF VALLINOID RECEPTOR TRPV1 RELATED DISORDERS |
摘要 |
The claimed invention provides benzimidazole derivatives antagonists of VR1, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I may be used in the treatment of osteoarthritis, chronic tendinitis, pelvic pain and peripheral neuropathy, gastroesophageal reflux disease, irritable bowel syndrome and overactive bladder. |
申请公布号 |
CA2660529(C) |
申请公布日期 |
2014.10.21 |
申请号 |
CA20072660529 |
申请日期 |
2007.08.10 |
申请人 |
ASTRAZENECA AB |
发明人 |
BROWN, WILLIAM;JOHNSTONE, SHAWN;LABRECQUE, DENIS |
分类号 |
C07D235/06;A61K31/4184;A61P1/04;A61P13/10;A61P19/02;A61P25/00;A61P29/00 |
主分类号 |
C07D235/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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