METHOD FOR REDUCING BLOOD LOSS IN MAJOR JOINT REPLACEMENT UNDER GENERAL ANAESTHESIA

摘要

FIELD: medicine.SUBSTANCE: haemodilution is performed with using crystalloid solutions, nitroglycerin and antihypertensive drugs. The antihypertensive drug is presented by using 5% pentamine intermittently administered after the beginning of the anaesthetic induction; if the effect of pentamine occurred to be inadequate, nitroglycerin is infused in an amount of 10 ml as a 0.1% solution diluted in crystalloid solution 200 ml for maintaining reference arterial blood pressure of 80/50 mm Hg. The nitroglycerin solution is kept to be administered until the wound is sutured, while the additional antihypertensive and blood loss reducing effect is ensured by spinal anaesthesia; as a haemostatic agent, an officinal solution of tranexamic acid 5-10 ml is intraoperatively intravenously introduced under an endoprosthesis bed.EFFECT: lower risk of postoperative complications and ensured controlled stable arterial blood pressure in the patient.2 ex