Compuestos derivados de pirimidindiona fusionada con pirazol, moduladores de receptores trpa1; composicion farmaceutica y uso para el dolor cronico, dolor reumatoide artritico o dolor osteoartritico (div. sol. 2315-11)

摘要

The present invention relates to a process for preparing a compound of formula (Id-1)
or a pharmaceutically acceptable salt thereof, which comprises
reacting a compound of formula (35) with amine compound of formula (18)
wherein,
R 1 and R 2 , which may be same or different, are independently selected from hydrogen and substituted or unsubstituted alkyl;
U is substituted or unsubstituted heterocycles selected from thiazole and isoxazole; and
V is substituted or unsubstituted aryl.