| 摘要 |
PROBLEM TO BE SOLVED: To provide use of parapoxviruses to prepare pharmaceuticals for the prophylaxis and the treatment of human illnesses associated with increased collagen deposition, the illnesses affecting inner organs such as the liver, and also skin and the appendages thereof, specifically liver fibrosis and/or liver cirrhosis resulting from viral hepatitis or ethanol-induced liver diseases and cystic fibrosis.SOLUTION: The present invention relates to the use of isolates of parapoxvirus obtained from strains D1701, orf-11, Greek orf strain 176, Greek orf strain 155, and New Zealand (NZ) or those parapoxviruses modified by passaging or adaptation to suitable cells for producing medicaments which have a preventive or curative effect on organ fibrosis in humans. |
