发明名称 COMPOSITIONS AND METHODS FOR THE INDUCTION AND TUNING OF GENE EXPRESSION
摘要 Disclosed herein are compositions of transcription activator-like effectors transcription factors and methods of using said compositions for inducing gene expression of mammalian genes.
申请公布号 US2014309177(A1) 申请公布日期 2014.10.16
申请号 US201414220116 申请日期 2014.03.19
申请人 Duke University 发明人 Perez-Pinera Pablo;Gersbach Charles
分类号 C12N5/071;A61K38/17 主分类号 C12N5/071
代理机构 代理人
主权项 1. A method of modulating mammalian gene expression in a cell, the method comprising contacting the cell with two or more transcription activator-like effector transcription factors (TALE-TFs) that bind to a target gene.
地址 Durham NC US