发明名称 |
COMPOSITIONS AND METHODS FOR THE INDUCTION AND TUNING OF GENE EXPRESSION |
摘要 |
Disclosed herein are compositions of transcription activator-like effectors transcription factors and methods of using said compositions for inducing gene expression of mammalian genes. |
申请公布号 |
US2014309177(A1) |
申请公布日期 |
2014.10.16 |
申请号 |
US201414220116 |
申请日期 |
2014.03.19 |
申请人 |
Duke University |
发明人 |
Perez-Pinera Pablo;Gersbach Charles |
分类号 |
C12N5/071;A61K38/17 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
1. A method of modulating mammalian gene expression in a cell, the method comprising contacting the cell with two or more transcription activator-like effector transcription factors (TALE-TFs) that bind to a target gene. |
地址 |
Durham NC US |