The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
申请公布号
CA2900433(A1)
申请公布日期
2014.10.16
申请号
CA20142900433
申请日期
2014.04.08
申请人
F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A.
发明人
HILPERT, HANS;HUMM, ROLAND;MUSER, THORSTEN;SCHNIDER, CHRISTIAN;WERMUTH, ROGER;WOLTERING, THOMAS