发明名称 |
Epsilon toxin epitopes from clostridium perfringens with reduced toxicity |
摘要 |
There is provided an epsilon toxin epitope polypeptide comprising a sequence of at least 10 contiguous amino acids from SEQ ID NO:3, the sequence comprising a mutation of at least one tyrosine residue compared to the equivalent sequence in SEQ ID NO:3, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:5 and having reduced toxicity compared with the toxicity of SEQ ID NO:5. The polypeptide is useful in a method of vaccinating a subject against developing a disease caused by |
申请公布号 |
AU2013239465(A1) |
申请公布日期 |
2014.10.16 |
申请号 |
AU20130239465 |
申请日期 |
2013.03.28 |
申请人 |
UNIVERSITY OF EXETER |
发明人 |
TITBALL, RICHARD W.;BOKORI-BROWN, MONIKA;NAYLOR, CLAIRE |
分类号 |
C07K14/33;A61K39/08 |
主分类号 |
C07K14/33 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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