发明名称 |
LOCAL DRUG DELIVERY DEVICES AND METHODS FOR TREATING CANCER |
摘要 |
Drug-eluting devices and methods for the treatment of tumors of the pancreas, biliary system, gallbladder, liver, small bowel, or colon, are provided. Methods include deploying a drug-eluting device having a film which includes a mixture of a degradable polymer and a chemotherapeutic drug, wherein the film has a thickness from about 2 µm to about 1000 µm, into a tissue site and releasing a therapeutically effective amount of the chemotherapeutic drug from the film to treat the tumor, wherein the release of the therapeutically effective amount of the drug from the film is controlled by in vivo degradation of the polymer at the tissue site. |
申请公布号 |
CA2944480(A1) |
申请公布日期 |
2014.10.16 |
申请号 |
CA20142944480 |
申请日期 |
2014.04.10 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE GENERAL HOSPITAL CORPORATION |
发明人 |
INDOLFI, LAURA;EDELMAN, ELAZER R.;LANGER, ROBERT S.;CLARK, JEFFREY W.;TING, DAVID T.;FERRONE, CRISTINA ROSA ANNAMARIA;LIGORIO, MATTEO |
分类号 |
A61L31/10;A61F2/04;A61K9/70 |
主分类号 |
A61L31/10 |
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