| 发明名称 |
METHOD FOR PURIFYING VIRUS-LIKE PARTICLES (VLP) |
| 摘要 |
The invention relates to a method for purifying compositions containing virus-like particles (VLP), wherein a VLP-containing composition is filtered through a filter medium, in particular through a membrane, having a molecular weight cut off (MWCO) of more than 30 kDa, and the cell culture supernatant of VLP-expressing cells is used as a VLP-containing composition. The invention further relates to a VLP-containing composition which can be produced by this method. |
| 申请公布号 |
US2014309408(A1) |
申请公布日期 |
2014.10.16 |
| 申请号 |
US201214236210 |
申请日期 |
2012.08.01 |
| 申请人 |
Demina Victoria;Manninga Heiko |
发明人 |
Demina Victoria;Manninga Heiko |
| 分类号 |
C07K1/34;C07K14/00;C07K1/22 |
主分类号 |
C07K1/34 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for purifying virus-like particles (VLPs), characterized in that a VLP-containing composition is filtered through a filter medium having an exclusion limit of more than 30 kDa to 1500 kDa, wherein the VLP-containing composition used is the supernatant of the culture of the VLP-expressing cells (cell culture supernatant). |
| 地址 |
Bonn DE |
