| 发明名称 |
METHOD OF COMBINATION THERAPY USING ANTI-C-MET ANTIBODY AND FGFR INHIBITOR |
| 摘要 |
Provided is a method for prevention or treatment of a cancer, comprising co-administering (a) an FGFR inhibitor and (b) an anti-c-Met antibody or antigen-binding fragment thereof to a subject in need thereof, wherein the anti-c-Met antibody or the antigen-binding fragment thereof specifically binds to an epitope comprising 5 or more contiguous amino acids within the SEMA domain of c-Met protein. |
| 申请公布号 |
US2014308284(A1) |
申请公布日期 |
2014.10.16 |
| 申请号 |
US201414242684 |
申请日期 |
2014.04.01 |
| 申请人 |
KIM BO GYOU;LEE JI MIN;KIM KYUNG AH;JEONG YUN JU |
发明人 |
KIM BO GYOU;LEE JI MIN;KIM KYUNG AH;JEONG YUN JU |
| 分类号 |
A61K39/395;A61K31/506;A61K31/519 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for prevention or treatment of a cancer, comprising co-administering (a) an FGFR inhibitor and (b) an anti-c-Met antibody or antigen-binding fragment thereof to a subject in need thereof,
wherein the anti-c-Met antibody or the antigen-binding fragment thereof specifically binds to an epitope comprising 5 or more contiguous amino acids within the SEMA domain of c-Met protein. |
| 地址 |
SEOUL KR |
