HUMAN ANTI-IP-10 ANTIBODY AND USE THEREOF

摘要

PROBLEM TO BE SOLVED: To provide a human anti-IP-10 antibody and the use thereof.SOLUTION: The invention relates to fully human antibodies and fragments thereof that bind to interferon-inducible-protein-10 (IP-10, CXCL10), thereby modulating interaction between IP-10 and its receptor CXCR3, and/or modulating biological activities of IP-10. The invention also relates to the use of such anti-IP-10 antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.