| 发明名称 |
COMPOSITIONS AND METHODS FOR REDUCING FOOD CRAVINGS |
| 摘要 |
Disclosed are compositions for reducing food cravings, comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound is an α-MSH agonist. Also disclosed are methods of reducing food cravings, comprising identifying an individual in need thereof and treating that individual to antagonize opioid receptor activity and to enhance α-MSH activity. |
| 申请公布号 |
US2014309252(A1) |
申请公布日期 |
2014.10.16 |
| 申请号 |
US201414207077 |
申请日期 |
2014.03.12 |
| 申请人 |
OREXIGEN THERAPEUTICS, INC. |
发明人 |
McKinney Anthony A.;Tollefson Gary;Cowley Michael A. |
| 分类号 |
A61K31/485;A61K31/138;A61K45/06;A61K31/137 |
主分类号 |
A61K31/485 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of reducing food cravings, comprising:
identifying a food-craving subject; and administering a first compound and a second compound to the subject in an amount that is effective to reduce food craving; wherein the first compound is selected from an opioid antagonist and an anticonvulsant; and wherein the second compound is an α-MSH activity enhancer. |
| 地址 |
unknown |
