Organs for Transplantation

摘要

The invention provides methods and compositions that improve the success of organ transplantation. The methods and compositions are directed to exposing a desired organ to stem cells prior to, during, and/or after transplantation. In one embodiment, the stem cells reduce the deleterious effects of ischemia on an organ designated to be harvested for transplantation or that has been harvested for transplantation. In another embodiment in which an organ designated for transplantation is perfused ex vivo, the method involves reducing ischemic reperfusion injury by perfusing the organ with a medium that contains stem cells.

主权项

1. A system comprising:
a database configured to associate a particular wireless device with at least one geographic area; a speed determiner configured to determine a change in location over time of the particular wireless device relative to the at least one geographic area; and an area watcher to selectively output a trigger message from a plurality of trigger messages for the a geographic area, the trigger message being selected from the plurality of trigger messages based on the determined change in location over time of the particular wireless device upon the particular wireless device one or more of entering and exiting the geographic area.