发明名称 Amino acid sequences directed against Rank-L and polypeptides comprising the same for the treatment of bone diseases and disorders
摘要 The present invention relates to amino acid sequences that are directed against RANK-L, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to 5 nucleic acids encoding such amino acid sequences and polypeptides; to methods for preparing such amino acid sequences and polypeptides; to hose cells expressing or capable of expressing such amino acid sequences or poly peptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses to such amino acid sequences or polypeptides, nucleic 10 acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes.
申请公布号 AU2012201229(B2) 申请公布日期 2014.10.16
申请号 AU20120201229 申请日期 2012.02.29
申请人 ABLYNX N.V. 发明人 BEIRNAERT, ELS;CORNELIS, SIGRID;HOOGENBOOM, HENDRICUS RENERUS JACOBUS MATTEUS
分类号 C07K16/22;A61P19/10 主分类号 C07K16/22
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