发明名称 |
METHODS FOR THE DETERMINATION OF A COPY NUMBER OF A GENOMIC SEQUENCE IN A BIOLOGICAL SAMPLE |
摘要 |
<p>Methods for the determination of a copy number of a target genomic sequence; either a target gene or genomic sequence of interest, in a biological sample are described. Various methods utilize a model drawn from a probability density function (PDF) for the assignment of a copy number of a target genomic sequence in a biological sample. Additionally, the methods provide for the determination of a confidence value for a copy number assigned to a sample based on attributes of the sample data. Accordingly, the various methods for the determination of a copy number provide the end user with significant information for the evaluation of a copy number of a target genomic sequence; either a gene or genomic sequence of interest.</p> |
申请公布号 |
EP2406400(A4) |
申请公布日期 |
2014.10.15 |
申请号 |
EP20100751309 |
申请日期 |
2010.03.09 |
申请人 |
LIFE TECHNOLOGIES CORPORATION |
发明人 |
LEONG, HARRISON M.;BARBACIORU, CATALIN;JANAWAY, GORDON A. |
分类号 |
C12Q1/68;G06F19/00;G06F19/20 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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