发明名称 |
METHODS FOR TREATING HYPERURICEMIA IN PATIENTS WITH GOUT USING HALOFENATE OR HALOFENIC ACID AND A SECOND URATE-LOWERING AGENT |
摘要 |
Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition associated with elevated serum uric acid levels comprising administering a composition comprising a first urate-lowering agent and a second urate-lowering agent. In some aspects the first urate-lowering agent is (-)- halofenate, (-)- halofenic acid, or a pharmaceutically acceptable salts thereof. In some aspects the second urate-lowering agent is an inhibitor of uric acid production, a uricosuric agent, a uricase, or a pharmaceutically acceptable salt thereof. |
申请公布号 |
KR20140121383(A) |
申请公布日期 |
2014.10.15 |
申请号 |
KR20147015169 |
申请日期 |
2011.11.04 |
申请人 |
CYMABAY THERAPEUTICS, INC. |
发明人 |
ROBERTS BRIAN K.;SAHA GOPAL CHANDRA;LAVAN BRIAN EDWARD;MCWHERTER CHARLES A. |
分类号 |
A61K31/192;A61K31/19;A61P19/06 |
主分类号 |
A61K31/192 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|