发明名称 |
Pharmaceutical composition for the treatment of osteoarthritis |
摘要 |
The invention relates to a method of treating or diagnosing a disease state mediated by monocytes. The method utilizes a composition comprising a conjugate or complex of the general formula <?in-line-formulae description="In-line Formulae" end="lead"?>Ab-X<?in-line-formulae description="In-line Formulae" end="tail"?> wherein the group Ab comprises a ligand that binds to monocytes, and when the conjugate is being used for treatment of the disease state, the group X comprises an immunogen, a cytotoxin, or a compound capable of altering monocyte function, and when the conjugate is being used for diagnosing the disease state, the group X comprises an imaging agent. |
申请公布号 |
EP1904183(B1) |
申请公布日期 |
2014.10.15 |
申请号 |
EP20060800015 |
申请日期 |
2006.07.05 |
申请人 |
PURDUE RESEARCH FOUNDATION |
发明人 |
LOW, PHILIP, STEWART;HILGENBRINK, ANDREW, RICHARD |
分类号 |
A61P29/00;A61K31/00;A61K38/19;A61K38/47;A61K47/48;A61K49/00;A61K51/04;A61P19/02 |
主分类号 |
A61P29/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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