发明名称 Pharmaceutical composition for the treatment of osteoarthritis
摘要 The invention relates to a method of treating or diagnosing a disease state mediated by monocytes. The method utilizes a composition comprising a conjugate or complex of the general formula <?in-line-formulae description="In-line Formulae" end="lead"?>Ab-X<?in-line-formulae description="In-line Formulae" end="tail"?> wherein the group Ab comprises a ligand that binds to monocytes, and when the conjugate is being used for treatment of the disease state, the group X comprises an immunogen, a cytotoxin, or a compound capable of altering monocyte function, and when the conjugate is being used for diagnosing the disease state, the group X comprises an imaging agent.
申请公布号 EP1904183(B1) 申请公布日期 2014.10.15
申请号 EP20060800015 申请日期 2006.07.05
申请人 PURDUE RESEARCH FOUNDATION 发明人 LOW, PHILIP, STEWART;HILGENBRINK, ANDREW, RICHARD
分类号 A61P29/00;A61K31/00;A61K38/19;A61K38/47;A61K47/48;A61K49/00;A61K51/04;A61P19/02 主分类号 A61P29/00
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