| 摘要 |
<p>Cyclohexanone is converted to its triperoxide in a flow reactor, wherein a first feed stream comprising formic acid, a second stream comprising hydrogen peroxide and a Bronsted acid and a third stream comprising cyclohexanone are mixed together. Alternatively, cyclohexanone triperoxide (TPO) is subjected to pyrolysis to form hexadecanolide and cyclopentadecane. Alternatively, cyclopentadecane is sequentially oxidised to give cyclopentadecanol and dehydrogenated to give cyclopentadecanone. Alternatively, a musk mixture is formed by mixing hexadecanolide and cyclopentadecanone. In a flow reactor, cyclohexanone in a synthetic isoparaffin solvent with dodecane (feed 1) was treated with formic acid (feed 2) and hydrogen peroxide / nitric acid (feed 3) to give cyclohexanone triperoxide. The flow reactor may provide reduced levels of the Baeyer-Villiger derived side products (e.g. É›-caprolactone and É›-formyloxycaproic acid).</p> |
