发明名称 |
HDAC 6 INHIBITOR-BASED METHODS FOR TREATING CANCER |
摘要 |
This invention provides methods for treating a subject afflicted with cancer, comprising concurrently administering (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as SAHA, doxorubicin or etoposide. This invention also provides methods for inducing the death of a transformed cell such as a cancer cell, comprising concurrently contacting the cell with (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as SAHA, doxorubicin or etoposide. |
申请公布号 |
CA2767697(C) |
申请公布日期 |
2014.10.14 |
申请号 |
CA20102767697 |
申请日期 |
2010.07.02 |
申请人 |
MEMORIAL SLOAN-KETTERING CANCER CENTER |
发明人 |
MARKS, PAUL A.;NAMDAR, MANDANA;XU, WEISHENG |
分类号 |
A61K31/7048;A61K31/167;A61K31/198;A61K31/422;A61K31/704;A61P35/00 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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