发明名称 |
Derivados del ácido 4-dimetilaminobutírico |
摘要 |
This invention relates to novel 4-dimethylaminobutyric acid derivatives of the formula wherein A1, A2, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments in methods for the treatment of diseases modulated by CPT2 inhibitors. |
申请公布号 |
ES2507089(T3) |
申请公布日期 |
2014.10.14 |
申请号 |
ES20090738022T |
申请日期 |
2009.04.20 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ANDJELKOVIC, MIRJANA;CECCARELLI, SIMONA M.;CHOMIENNE, ODILE;KAPLAN, GERALD LEWIS;MATTEI, PATRIZIO;TILLEY, JEFFERSON WRIGHT |
分类号 |
C07C233/51;A61K31/197;A61K31/381;A61K31/426;A61K31/4406;A61P3/06;A61P3/08;A61P9/12;C07C235/12;C07C235/20;C07C237/12;C07C275/16;C07D213/55;C07D277/30;C07D333/24 |
主分类号 |
C07C233/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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