Repair and/or reconstitution of invertebral discs

摘要

This invention relates to a method for repair and reconstitution of invertebral discs in a subject which involves administration of STRO-1+ multipotent cells. The method of the invention is useful in the treatment of spinal conditions characterized by degeneration of the invertebral disc.

主权项

1. A method for treating a degenerated intervertebral disc in a subject, the method comprising administering to the degenerated intervertebral disc a population of cells which has been enriched for STRO-1bright multipotential cells and/or progeny cells thereof, wherein administering the cells causes regeneration and/or repair of the degenerated intervertebral disc, and wherein the STRO-1bright multipotential cells and/or progeny cells thereof are administered into the nucleus pulposus of the degenerated intervertebral disc.