| 发明名称 |
Multimeric peptidomimetic fibrosis specific dual-modality probes |
| 摘要 |
The present invention describes dual-modality probes. In particular, the present invention discloses fibrosis specific multimeric small-molecule peptidomimetic dual-modality MRI and optical probes. |
| 申请公布号 |
US8858913(B2) |
申请公布日期 |
2014.10.14 |
| 申请号 |
US201213595515 |
申请日期 |
2012.08.27 |
| 申请人 |
|
发明人 |
Bhushan Kumar Ranjan;Misra Preeti |
| 分类号 |
A61K49/00;A61K49/10;A61B5/00;A61B8/00;A61B10/00 |
主分类号 |
A61K49/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A dual-modality probe having a formula selected from the group consisting of:wherein R is L1, L2, L3, L4, L5 and L6 are linkers; IRDye is a near infrared dye with wavelength in the range of 700-900 nm;andis a metal chelate independently selected from: |
| 地址 |
|
