Pixel-type biological analysis device, biosensor, and fabrication processes thereof

摘要

The disclosure relates to a pixel-type biological analysis device comprising a photosensitive layer, a capture mixture for the capture of targeted proteins, the capture mixture being placed on an external surface of the photosensitive layer and comprising a protein probe grafted to a hydrogel, collection means for collecting photoelectrons in the photosensitive layer, and reading and treatment means of an electrical quantity supplied by the collection means, for the supply of a characteristic value of a luminous intensity detected by the photosensitive layer.

主权项

1. A pixel-type biological analysis device comprising:
a photosensitive layer; a capture mixture configured to capture targeted proteins, the capture mixture being positioned on an external surface of the photosensitive layer and including a hydrogel and a protein probe grafted to the hydrogel; a photoelectron collector in the photosensitive layer and configured to collect photoelectrons and provide an electrical quantity, wherein the photoelectron collector comprises:
a first portion configured to detect an incident luminous intensity coming from the capture mixture and supply a first electrical quantity; anda second portion configured to supply a second electrical quantity and protected against all sources of luminous intensity, including the incident luminous intensity coming from the capture mixture; and read circuitry configured to read the electrical quantity and supply a read signal characteristic of a luminous intensity detected by the photosensitive layer, wherein the read circuitry includes an amplifier having a first input coupled to the first portion and a second input coupled to the second portion, the amplifier being configured to supply a read signal based on the first and second electrical quantities, the read signal being characteristic of the incident luminous intensity detected by the first portion.