发明名称 |
Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis |
摘要 |
A combination therapy for treating osteoarthritis is disclosed. The combination therapy includes the co-administration of a steroid and Zoledronic Acid. The coadministration of a steroid decreases the production of cytokines, and, therefore, decreases the pro-inflammatory effects of Zoledronic Acid. The co-administration of Zoledronic Acid with steroids treats osteoarthritis, and helps to prevent the onset of osteoarthritis in patients at risk for osteoarthritis. |
申请公布号 |
US8859530(B2) |
申请公布日期 |
2014.10.14 |
申请号 |
US201414202950 |
申请日期 |
2014.03.10 |
申请人 |
Voltarra Pharmaceuticals, Inc. |
发明人 |
Desai Ketan |
分类号 |
A61K31/66;A61K31/12;A61K31/675;A61K31/573;A61K45/06 |
主分类号 |
A61K31/66 |
代理机构 |
Hultquist, PLLC |
代理人 |
Hultquist, PLLC ;Bradin David |
主权项 |
1. A method for treating osteoarthritis in a patient in need thereof, the method comprising intravenous administration to the patient a combination of prednisolone or a pharmaceutically acceptable salt thereof and Zoledronic acid or a pharmaceutically acceptable salt thereof in a single infusion. |
地址 |
Bethlehem PA US |