| 发明名称 | Diagnostic assays for chordopoxviruses | ||
| 摘要 | This disclosure relates to compositions and methods of their use in detection and identification of a chordopoxvirus in a sample, such as diagnosis of an infection in a subject. The compositions and methods allow for detection and identification of all non-avian low-GC content chordopoxviruses, identification of most known high-GC content chordopoxvirus, and species-specific detection of Canarypox virus, Fowlpox virus, and Sealpox virus. | ||
| 申请公布号 | US8859742(B2) | 申请公布日期 | 2014.10.14 |
| 申请号 | US201013505719 | 申请日期 | 2010.11.02 |
| 申请人 | The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention | 发明人 | Li Yu;Damon Inger K.;Zhao Hui |
| 分类号 | C12Q1/68;C12Q1/70 | 主分类号 | C12Q1/68 |
| 代理机构 | Klarquist Sparkman, LLP | 代理人 | Klarquist Sparkman, LLP |
| 主权项 | 1. A pair of isolated nucleic acid molecules, the respective sequences of which: consist of SEQ ID NOs: 13 and 14; consist of SEQ ID NOs: 20 and 21; consist of SEQ ID NOs: 22 and 23; consist of SEQ ID NOs: 25 and 26; consist of SEQ ID NOs: 28 and 29; or comprise SEQ ID NO: 28 and comprise a nucleic acid sequence at least 95% identical to SEQ ID NO: 29, wherein at least one of the pair of isolated nucleic acid molecules is operably linked to a detectable label and wherein the detectable label comprises a radioactive isotope, a chemiluminescent or fluorescent agent, a hapten, or an enzyme. | ||
| 地址 | Washington DC US | ||