发明名称 |
DETECÇÃO DE ISÔMEROS USANDO ESPECTROMETRIA DE MASSA DE DERIVATIZAÇÃO DIFERENCIAL. |
摘要 |
<p>Methods of evaluating molecular isomers of branched-chain amino acids are featured. The methods can include: derivatizing one or more molecular isomers of branched-chain amino acids in a sample comprising a branched-chain amino acid labeled with one or more heavy atoms as a first standard; adding, to the sample, after derivatization, a nonderivatized or derivatized branched chain amino acid that is labeled with one or more heavy atoms, as a second standard; evaluating the sample using tandem mass spectrometry; and detecting peaks indicative of derivatized and nonderivatized forms of one or more branched-chain amino acids in the sample.</p> |
申请公布号 |
BRPI0811500(A2) |
申请公布日期 |
2014.10.14 |
申请号 |
BR2008PI11500 |
申请日期 |
2008.05.05 |
申请人 |
PERKINELMER HEALTH SCIENCES, INC. |
发明人 |
BLAS CERDA;ALEX CHERKASSKIY;YIJUN LI |
分类号 |
B01L99/00;G01N33/00;C40B20/08 |
主分类号 |
B01L99/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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