Process for production of L-amino acid

摘要

Provided is a novel process for producing an L-amino acid using a microorganism belonging to the genus Escherichia. According to the present invention, a process for producing an L-amino acid comprising; culturing a microorganism in which an activity of the protein of any of the following [1]-[3] is increased compared with that of the parent strain in a medium, producing and accumulating the L-amino acid in the medium, and recovering the L-amino acid from the medium:
[1] a protein comprising the amino acid sequence shown in SEQ ID NO: 2[2] a protein consisting of an amino acid sequence in which one or more amino acids are deleted, substituted or added in the amino acid sequence shown in SEQ ID NO: 2, and having YeiG activity[3] a protein consisting of an amino acid sequence having 80% or more homology to the amino acid sequence shown in SEQ ID NO: 2, and having YeiG activity.

主权项

1. A process for producing an L-amino acid comprising:
culturing a microorganism in which an activity of a protein is increased compared to the parent strain in a medium, producing and accumulating the L-amino acid in the medium, and recovering the L-amino acid from the medium, wherein the protein is [1] a protein comprising the amino acid sequence shown in SEQ ID NO:2, or [2] a homologous protein consisting of an amino acid sequence having 95% or more identity to the amino acid sequence shown in SEQ ID NO: 2, and having YeiG activity.