Treatment drug for autoimmune diseases and allergic diseases

摘要

The present invention provides an agent for the prophylaxis or therapy of autoimmune diseases or allergic diseases, which contains an anti-Embigin antibody, particularly an anti-Embigin antibody showing cytotoxicity or a cytotoxicity inducing activity, an agent for the prophylaxis or therapy of diseases involving Th17 cell, and a cytotoxic agent to Th17 cell. In addition, an agent for detection of Th17 cell, which contains an anti-Embigin antibody, a convenient detection method of Th17 cell, which uses the agent, a method of efficiently delivering a drug and the like in a Th17 cell selective manner, which uses an anti-Embigin antibody, and a drug delivery system to Th17 cell are provided.

主权项

1. A method for the prophylaxis and/or therapy of a disease associated with Th17 cells in a subject, comprising administering an effective amount of an anti-Embigin antibody having cytotoxicity or cytotoxicity inducing activity to the subject, wherein the disease associated with Th17 cells is selected from the group consisting of multiple sclerosis, psoriasis, rheumatism, chronic noninfectious uveitis, and glomerulonephritis.