Heterocyclic inhibitors of histamine receptors for the treatment of disease

摘要

The present invention relates to salts, hydrates, and polymorphs of bicyclic heteroaryl compounds, and pharmaceutical compositions thereof, which may be useful as inhibitors of H4R for the treatment or prevention of diseases including allergic rhinitis.

主权项

1. A compound which is a salt, hydrate, or polymorph of structural Formula (XII) wherein:
X8 is chosen from CH and N;m and n are each an integer chosen from 1 and 2, and m=n;R24 is chosen from lower amino, lower alkylamino, and lower alkyl;Y is chosen from a counterion and null; andZ is a chosen from a hydrate and null.