发明名称 |
Hydrate of 1-{(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-5,8-di-hydropyrido[3,4-D]pyrimidin-7(6H)-yl]-4-oxobutyl}-5,5-difluoro-piperidin-2-one tartrate |
摘要 |
The present invention relates to 1.5 hydrate of of 1-{(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl}-5,5-difluoropiperidin-2-one tartrate, a process for preparing the same, and a pharmaceutical composition for inhibiting DPP-IV, which comprises said compound as the active component. |
申请公布号 |
US8859567(B2) |
申请公布日期 |
2014.10.14 |
申请号 |
US201113879571 |
申请日期 |
2011.10.31 |
申请人 |
LG Life Sciences Ltd. |
发明人 |
Park Ki Sook;Yun Jung Min;Kim Bong Chan;Kim Kyu Young;Lee Ji Hye |
分类号 |
C07D471/04;A61K31/519 |
主分类号 |
C07D471/04 |
代理机构 |
Birch, Stewart, Kolasch & Birch, LLP |
代理人 |
Birch, Stewart, Kolasch & Birch, LLP |
主权项 |
1. 1.5 Hydrate of 1-{(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl}-5,5-difluoropiperidin-2-one tartrate salt having a water content in the range of 3.5-5.5%. |
地址 |
Seoul KR |