发明名称 STABILIZED FORMULATIONS CONTAINING ANTI-ANG2 ANTIBODIES
摘要 The present disclosure provides pharmaceutical formulations comprising an antibody that specifically binds to angiopoietin 2 (Ang-2). The formulations may contain, in addition to an anti-Ang-2 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present disclosure exhibit a substantial degree of antibody stability after storage for several months and after being subjected to thermal and other physical stress.
申请公布号 PH12014501628(A1) 申请公布日期 2014.10.13
申请号 PH12014501628 申请日期 2014.07.15
申请人 REGENERON PHARMACEUTICALS, INC. 发明人 WALSH, SCOTT;DIX, DANIEL
分类号 A61K39/395;A61K47/06;A61K47/26;C07K16/22 主分类号 A61K39/395
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