<p>The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.</p>
申请公布号
MX2014011000(A)
申请公布日期
2014.10.13
申请号
MX20140011000
申请日期
2013.03.13
申请人
MERCK SHARP & DOHME CORP.
发明人
YIN, JIANGUO;KUO, SHEN-CHUN;BELYK, KEVIN M.;YASUDA, NOBUYOSHI;CLEATOR, EDWARD;MALIGRES, PETER EMMANUEL;XIANG, BANGPING