发明名称 SUBSTITUTED CARBAMOYLMETHYLAMINO ACETIC ACID DERIVATIVES AS NOVEL NEP INHIBITORS NEP
摘要 The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 6 , A 1 , A 2 , X 1 , sand m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
申请公布号 HK1170475(A1) 申请公布日期 2014.10.10
申请号 HK20120110737 申请日期 2012.10.26
申请人 NOVARTIS AG 发明人 IWAKI, YUKI;KAWANAMI, TOSHIO;KSANDER, GARY MICHAEL;MOGI, MUNETO
分类号 C07D;A61K;A61P 主分类号 C07D
代理机构 代理人
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