BISPECIFIC ANTI-CMET/ANTI-EGFR ANTIBODIES

摘要

The present invention provides an anti-c-Met/anti-EGFR bispecific antibody, a pharmaceutical composition for preventing and/or treating cancer including the same, and an anti EGFR scFv fragment. The anti-c-Met/anti-EGFR bispecific antibody includes an anti-c-Met antibody or an antigen-binding fragment thereof, and anti-EGFR antibody or an antigen-binding fragment thereof. The anti-c-Met antibody is bound specifically to an epitope composed of five or more amino acids that are consecutive in a SEMA domain (SEQ ID NO. 79) of c-Met protein.